Xeomin (1x100iu): What is it and How Xeomin Compares to BOTOX®
Xeomin (1x100iu) (incobotulinumtoxinA), made by Merz Pharmaceuticals, is approved by the US FDA for the treatment of adults with cervical dystonia or blepharospasm and Moderate to severe frown lines between the eyebrows. IncobotulinumtoxinA is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.
FDA approval of Xeomin (1x100iu), was based on the results of two U.S. clinical trials. A study cited in the Journal of Neurological Sciences on the efficacy and safety of XEOMIN found it showed “non-inferiority” to Botox when used in the same doses to treat cervical dystonia. It concluded that XEOMIN is a safe and effective treatment for the disorder.
Xeomin has now been approved for some cosmetic indications – Moderate to severe frown lines between the eyebrows. Similiar to other drugs in this category, including Botox and Dysport, that also have FDA approval for the treatment of facial wrinkles. Now that Xeomin is available and FDA approved, doctors can use it both on-label and off-label to treat the same facial lines treated by Botox and Dysport, including frown lines, crow’s feet and forehead wrinkles.
Worldwide, more than 84,000 people have been treated with Xeomin injections. The U.S. is actually the 20th country to approve this new drug. It is available in 50-unit and 100-unit vials.
Can Xeomin be used to treat muscle spasms and pain?
XEOMIN is an effective drug that has been available by prescription since 2005, to treat pain in the head and neck pain symptoms that occur during Cervical Dystonia. It is also used to treat muscle spasms in the eyelid which is otherwise known as Blepharospasm. The Blepharospasm is usually an effect of Botox.
How does Xeomin work on muscles?
Once XEOMIN has been injected into the muscles, it starts to inhibit acetylcholine from being released. It is this chemical which makes fibers in the muscle to contract, so without acetylcholine, muscles will contract less, resulting in less spasms and discomfort to the individual.
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